Alveolar microlithiasis is a very rare disease with an autosomal recessive inheritance, characterized by the deposition of calcium phosphate in the alveoli.
Shows a slight male predilection, common in patients < 30 years of age.
Modality of choice
Chest radiograph and CT.
Multiple calcified micronodules predominantly in the lung bases, coalescing over time to form dense consolidations and ground-glass opacities accompanied by septal thickening in a crazy-paving pattern.
Radiograph in the early stage shows increased lung markings with a micronodular pattern predominantly in the lower lung.
Advanced stage shows dense, irregular opacities predominantly in the lower lung.
CT in the early stage shows calcified micronodules predominantly in the lower lung, distributed randomly or along the septa and peribronchovascular structures.
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